Keyhole limpet Hemocyanin
血蓝蛋白/钥孔血蓝蛋白（进口）
| 英文名称 | Keyhole limpet Hemocyanin |
| 中文名称 | 血蓝蛋白/钥孔血蓝蛋白（进口） |
| 别 名 | Keyhole limpet; keyhole limpet hemocyanin; Hemocyanin from Megathura crenulata (keyhole limpet); Hemocyanin from Limulus polyphemus hemolymph; hemocyanin; haemocyanin; 载体蛋白; 血兰蛋白; 钥孔戚血蓝蛋白; 血蓝蛋白(KLH); 血清朊; 血蓝素; 匙孔嘁血蓝蛋白; |
| 性 状 | lyophilized powder |
| 物 种 | Keyhole limpet |
| 序 列 | Purified native protein |
| 内毒素 | Not analyzed |
| 活性 | Not tested |
| 保存条件 | Stored at 2-8℃. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 | Keyhole limpet hemocyanin (KLH) is used extensively as a carrier protein in the production of antibodies for research, biotechnology and therapeutic applications. Haptens are substances with a low molecular weight such as peptides, small proteins and drug molecules that are generally not immunogenic and require the aid of a carrier protein to stimulate a response from the immune system in the form of antibody production. KLH is the most widely employed carrier protein for this purpose. KLH is an effective carrier protein for several reasons. Its large size and numerous epitopes generate a substantial immune response, and abundance of lysine residues for coupling haptens allows a high hapten:carrier protein ratio, increasing the likelihood of generating hapten-specific antibodies. In addition, because KLH is derived from the limpet, a gastropod, it is phylogenetically distant from mammalian proteins, thus reducing false positives in immunologically-based research techniques in mammalian model organisms. KLH can also be a challenging molecule to work with because of its propensity to aggregate and precipitate. Aggregates remain immunogenic, but limit the ability to conjugate haptens, and are difficult to manipulate in the laboratory. A high-quality KLH preparation with clear opalescent blue color is the best indicator of KLH solubility. CAS：9013-72-3 分子量：8000-9000kDa Type: Type VIII Form: lyophilized powder Composition: Protein, ≥85% biuret Copper content: 0.10-0.20% (ICP-atomic emission) 来源：Limulus polyphemus hemolymph 外观：白色带微蓝色冻干粉 介绍：血蓝蛋白是在某些软体动物、节肢动物(蜘蛛和甲壳虫)的血淋巴中发现的一种游离的蓝 色呼吸色素。血蓝蛋白含两个直接连接多肽链的铜离子，与含铁的血红蛋白类似，它易于氧结合，也易与氧解离，是已知的惟一可与氧可逆结合的铜蛋白，氧化时呈青绿色，还原时呈白色。节肢动 物中血蓝蛋白的含量比软体动物的含量要高。具有载氧功能、抗病毒活性、抗菌活性、凝血功能。 用途：血蓝蛋白是具有高度免疫原性的蛋白大分子，作为载体蛋白用于免疫原的制备，交联于半抗原和其他抗原，增强它们的免疫原性。 SIGMA：H1757 |
本产品仅供科研使用.请勿用于医药,不能用于临床治疗诊断使用！