uPA抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
uPA抗体

uPA抗体

商家询价

产品名称： uPA抗体

英文名称： uPAAntibody

产品编号： XY17968-1-

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 UPA抗体Applications

Tested Applications: ELISA, WB, IHC, IP, IF
Cited applications WB
Specificity Reaction: Human,Mouse,Rat; Other species are not tested.Please decide the specificity by homology
Cited species Mouse
Positive WB detected in HeLa cells, A375 cells, human brain tissue
Positive IP detected in HeLa cells
Positive IHC detected in Human skin tissue, human lung tissue, human ovary tissue
Positive IF detected in HeLa cells
Recommended dilution WB : 1:200-1:2000
IP : 1:500-1:5000
IHC : 1:20-1:200
IF : 1:20-1:200
 UPA抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Images
Prev12NextView more validation data
  • 17968-1-AP;HeLa cellsHeLa cells were subjected to SDS PAGE followed by western blot with 17968-1-AP(uPA antibody) at dilution of 1:500
  • 17968-1-AP;human skinImmunohistochemical of paraffin-embedded human skin using 17968-1-AP(uPA antibody) at dilution of 1:50 (under 40x lens)
  • 17968-1-AP;HeLa cellsIP Result of anti-uPA (IP:17968-1-AP, 4ug; Detection:17968-1-AP 1:1000) with HeLa cells lysate 2800ug.
  • 17968-1-AP;HeLa cellsImmunofluorescent analysis of HeLa cells using 17968-1-AP( uPA Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Product Information UPA抗体
Source: Rabbit Purify: Antigen affinity purification
IsoType: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
Immunogen Information
Immunogen: UPA fusion protein ag11813 Full Name: Plasminogen activator, urokinase
Caculated Molecular
Weight:		 431aa,49 kDa Observed Molecular 
Weight:		 54 kDa
GenbankNo BC013575 GeneID: 5328
Symbol PLAU Synonyms ATF, PLAU, U plasminogen activator, uPA, URK
Background

PLAU(Urokinase-type plasminogen activator) is also named as uPA and belongs to the peptidase S1 family.UPA initiates a proteolytic cascade, which degrades extracellular matrix during tissue growth and remodelling.The secreted proform of UPA is activated after binding to a specific high affinity cell surface receptor. Secreted UPA is exposed to rapid inactivation in the pericellular space by plasminogen activator inhibitor-1 (PAI-1), which is stored in the extracellular matrix bound to vitronectin(PMID:9665342).It has 2 isoforms produced by alternative splicing.Defects in PLAU are the cause of Quebec platelet disorder (QPD). UPA抗体

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