FITC标记的12号染色体开放阅读框24抗体
产品名称： FITC标记的12号染色体开放阅读框24抗体
英文名称： Anti-C12ORF24/FITC
产品编号： HZ-9945R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-C12ORF24/FITC Conjugated antibody
FITC标记的12号染色体开放阅读框24抗体
| 产品编号 | bs-9945R-FITC |
| 英文名称 | Anti-C12ORF24/FITC |
| 中文名称 | FITC标记的12号染色体开放阅读框24抗体 |
| 别 名 | Chromosome 12 open reading frame 24; HSU79274; Hypothetical protein LOC29902; Protein predicted by clone 23733; F216A_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 心血管 细胞生物 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Cow, Rabbit, Sheep, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 31kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human C12ORF24 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The C12orf24 gene product has been provisionally designated C12orf24 pending further characterization. Similarity: Belongs to the FAM216 family. Database links: Entrez Gene: 29902 Human SwissProt: Q8WUB2 Human Unigene: 436618 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
在1亿3200万个碱基中编码超过1100个基因，染色体12构类基因组的4.5%。许多骨骼畸形与染色体12有关，包括软骨发育不良、软骨发育不全和最不典型增生。努南综合征，包括心脏和面部发育缺陷之间的主要症状，是由突变形式的PTPN11基因产物，SH-PTP2。第12染色体也是同源框基因簇的家系，其编码重要的转录因子用于形态发生，以及编码C型凝集素蛋白的自然杀伤复合基因簇，其介导NK细胞对MHC-I相互作用的应答。12P三体导致面部发育缺陷、癫痫发作和许多其他症状的严重程度取决于嵌合体的程度，并且在完全三体性的情况下最为严重。C12ORF24基因产物已暂时指定为C12ORF24，有待进一步鉴定。