FITC标记的腺苷酸硫酸激酶1抗体
产品名称： FITC标记的腺苷酸硫酸激酶1抗体
英文名称： Anti-PAPSS1/FITC
产品编号： HZ-9029R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-PAPSS1/FITC Conjugated antibody
FITC标记的腺苷酸硫酸激酶1抗体
| 产品编号 | bs-9029R-FITC |
| 英文名称 | Anti-PAPSS1/FITC |
| 中文名称 | FITC标记的腺苷酸硫酸激酶1抗体 |
| 别 名 | Adenylyl-sulfate kinase; Adenylylsulfate 3''-phosphotransferase; APS kinase; ATP-sulfurylase; ATPSK 1; ATPSK1; Bifunctional 3' phosphoadenosine 5' phosphosulfate synthetase 1; PAPS synthase 1; PAPS synthetase 1; PAPS1_HUMAN; PAPSS 1; PAPSS; PAPSS1; SAT; SK 1; SK1; Sulfate adenylate transferase; Sulfurylase kinase 1; 3 prime phosphoadenosine 5 prime phosphosulfate synthase 1; 3' phosphoadenosine 5' phosphosulfate synthase 1; 3''-phosphoadenosine-5''-phosphosulfate synthase; Adenosine-5''-phosphosulfate 3''-phosphotransferase. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 69kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PAPSS1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Three-prime-phosphoadenosine 5-prime-phosphosulfate (PAPS) is the sulfate donor cosubstrate for all sulfotransferase (SULT) enzymes (Xu et al., 2000 [PubMed 10679223]). SULTs catalyze the sulfate conjugation of many endogenous and exogenous compounds, including drugs and other xenobiotics. In humans, PAPS is synthesized from adenosine 5-prime triphosphate (ATP) and inorganic sulfate by 2 isoforms, PAPSS1 and PAPSS2 (MIM 603005).[supplied by OMIM, Mar 2008]. Function: Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate (PAPS: activated sulfate donor used by sulfotransferase). In mammals, PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate-activation pathway. Also involved in the biosynthesis of sulfated L-selectin ligands in endothelial cells. Tissue Specificity: Expressed in testis, pancreas, kidney, thymus, prostate, ovary, small intestine, colon, leukocytes and liver. Also expressed in high endothelial venules (HEV) cells and in cartilage. Similarity: In the N-terminal section; belongs to the APS kinase family. In the C-terminal section; belongs to the sulfate adenylyltransferase family. Database links: Entrez Gene: 504439 Cow Entrez Gene: 9060 Human Entrez Gene: 9061 Human Entrez Gene: 23971 Mouse Entrez Gene: 295443 Rat Omim: 603262 Human SwissProt: O43252 Human SwissProt: O95340 Human SwissProt: O88428 Mouse SwissProt: Q60967 Mouse Unigene: 368610 Human Unigene: 524491 Human Unigene: 203916 Mouse Unigene: 244912 Mouse Unigene: 3507 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
三个碱性磷酸腺苷5-磷酸磷酯（PAPs）是所有磺基转移酶（SULT）酶的硫酸供体共基质（Xu等，2000 [PubMed 10679223 ]）。SULTS催化许多内源性和外源性化合物的硫酸盐结合，包括药物和其他外来物质。在人类中，PAP由2种亚型、PAPSS1和PAPSS2（MIM 603005）提供，由腺苷5-磷酸三磷酸（ATP）和无机硫酸盐合成。