FITC标记的细胞色素c氧化酶VIIA亚型2抗体
产品名称: FITC标记的细胞色素c氧化酶VIIA亚型2抗体
英文名称: Anti-COX7A2/FITC
产品编号: HZ-0264R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-COX7A2/FITC Conjugated antibody
FITC标记的细胞色素c氧化酶VIIA亚型2抗体
产品编号 | bs-0264R-FITC |
英文名称 | Anti-COX7A2/FITC |
中文名称 | FITC标记的细胞色素c氧化酶VIIA亚型2抗体 |
别 名 | COX7A2; Cytochrome c oxidase polypeptide VIIa-liver/heart; mitochondrial precursor (Cytochrome c oxidase subunit VIIa-L) (VIIaL); CX7A2_HUMAN. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 肿瘤 细胞生物 免疫学 信号转导 线粒体 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Cow, Sheep, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 6.7kDa |
细胞定位 | 细胞膜 线粒体 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human COX7A2 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Cytochrome c oxidase, the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes, and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (liver isoform) of subunit VIIa, with this polypeptide being present in both muscle and non-muscle tissues. In addition to polypeptide 2, subunit VIIa includes polypeptide 1(muscle isoform), which is present only in muscle tissues, and a related protein, which is present in all tissues. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4 and 14. [provided by RefSeq, Oct 2009]. Function: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. Subcellular Location: Mitochondrion inner membrane Similarity: Belongs to the cytochrome c oxidase VIIa family. Database links: Entrez Gene: 1347 Human o Entrez Gene: 12866 Mouse
o Entrez Gene: 29507 Rat o Omim: 123996 Human o SwissProt: P14406 Human o SwissProt: P48771 Mouse o SwissProt: P35171 Rat o Unigene: 70312 Human o Unigene: 152627 Mouse o Unigene: 1745 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
细胞色素C氧化酶是线粒体呼吸链的末端成分,催化从细胞色素C还原为氧的电子传递。该组分是由线粒体基因编码的三个催化亚基和由核基因编码的多个结构亚基组成的杂合复合体。线粒体编码亚基在电子传递中起作用,而核编码亚基可能在调节和组装复合物中起作用。该核基因编码亚单位VIIa的多肽2(肝脏亚型),该多肽存在于肌肉和非肌肉组织中。除了多肽2之外,亚单位VIIa包括多肽1(肌肉亚型),其仅存在于肌肉组织中,以及存在于所有组织中的相关蛋白。选择性剪接导致多个转录变体。在4和14号染色体上已鉴定出相关的假基因。[ RefSeq,OCT 2009 ]提供。