FITC标记的KIAA1618蛋白抗体
产品名称： FITC标记的KIAA1618蛋白抗体
英文名称： Anti-KIAA1618/FITC
产品编号： HZ-17018R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-KIAA1618/FITC Conjugated antibody
FITC标记的KIAA1618蛋白抗体
| 英文名称 | Anti-KIAA1618/FITC |
| 中文名称 | FITC标记的KIAA1618蛋白抗体 |
| 别 名 | ALK lymphoma oligomerization partner on chromosome 17; ALO17; RN213_HUMAN; Hypothetical protein LOC57714; Protein ALO17. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 591kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KIAA1618 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: There are three isoforms. A chromosomal aberration involving KIAA1618 is associated with anaplastic large-cell lymphoma (ALCL). Translocation t(2;17)(p23;q25) with ALK. Function: Probable E3 ubiquitin-protein ligase that may play a role in angiogenesis. May also have an ATPase activity. Subcellular Location: Cytoplasm Tissue Specificity: Widely expressed (at protein level). Post-translational modifications: Autoubiquitinates. DISEASE: Moyamoya disease 2 (MYMY2) [MIM:607151]: A progressive cerebral angiopathy characterized by bilateral intracranial carotid artery stenosis and telangiectatic vessels in the region of the basal ganglia. The abnormal vessels resemble a 'puff of smoke' (moyamoya) on cerebral angiogram. Affected individuals can develop transient ischemic attacks and/or cerebral infarction, and rupture of the collateral vessels can cause intracranial hemorrhage. Hemiplegia of sudden onset and epileptic seizures constitute the prevailing presentation in childhood, while subarachnoid bleeding occurs more frequently in adults. {ECO:0000269|PubMed:21048783, ECO:0000269|PubMed:21799892}. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry. Similarity: Contains 1 RING-type zinc finger. Database links: Entrez Gene: 57714 Human SwissProt: Q9HCF4 Human Unigene: 514554 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application |
有三种异构体。染色体异常涉及KIAA1618与间变性大细胞淋巴瘤（ALCL）有关。转移性T（2；17）（p23；q25）与ALK。