FITC标记的高尔基体卷曲螺旋蛋白1抗体
产品名称： FITC标记的高尔基体卷曲螺旋蛋白1抗体
英文名称： Anti-GCC1/FITC
产品编号： HZ-13310R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-GCC1/FITC Conjugated antibody
FITC标记的高尔基体卷曲螺旋蛋白1抗体
| 英文名称 | Anti-GCC1/FITC |
| 中文名称 | FITC标记的高尔基体卷曲螺旋蛋白1抗体 |
| 别 名 | GCC protein; GCC1P; GCC88; Golgi coiled coil 1; Golgi coiled coil protein 1; GRIP and coiled coil domain containing 1; Peripheral membrane Golgi protein; GCC1_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 88kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GCC1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: GCC1 is a 775 amino acid cytoplasmic and peripheral membrane protein of the Golgi apparatus. Involved in maintenance of Golgi structure, GCC1 is essential for retrograde transport of cargo from the early endosomes to the trans-Golgi network. GCC1 contains one GRIP domain and is encoded by a gene that maps to human chromosome 7q32.1. Chromosome 7 houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. Function: GCC1 is a peripheral membrane protein and is sensitive to brefeldin A. GCC1 contains a GRIP domain which is thought to be used in targeting. It may play a role in the organization of trans-Golgi network subcompartment involved with membrane transport. Subcellular Location: Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Similarity: Contains 1 GRIP domain. Database links: UniProtKB/Swiss-Prot: Q96CN9.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
GCC1是高尔基体的775氨基酸胞质和外周膜蛋白。GCC1参与高尔基体结构的维护，对于货物从早期内含体逆行运输到跨高尔基体网络是必不可少的。GCC1包含一个握持域，并由映射到人类染色体7q32.1的基因编码。染色体7包含1000多个基因，占人类基因组的近5%，与成骨不全、Pendred综合征、Lissencephaly、Citrullinemia和Shwachman-Diamond综合征有关。