FITC标记的范可尼综合征相关锌指蛋白抗体
产品名称： FITC标记的范可尼综合征相关锌指蛋白抗体
英文名称： Anti-TZFP/ZNF538/FITC
产品编号： HZ-8007R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-TZFP/ZNF538/FITC Conjugated antibody
FITC标记的范可尼综合征相关锌指蛋白抗体
| 英文名称 | Anti-TZFP/ZNF538/FITC |
| 中文名称 | FITC标记的范可尼综合征相关锌指蛋白抗体 |
| 别 名 | FANCC interacting protein; FANCC-interacting protein; Fanconi anemia zinc finger protein; FAXF; FAZF; OTTHUMP00000045790; repressor of GATA; Rog; Testis zinc finger protein; ZBT32_HUMAN; Zbtb32; ZBTB32 protein; Zinc finger and BTB domain containing 32; Zinc finger and BTB domain-containing protein 32; Zinc finger protein 538; ZNF538. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 转录调节因子 锌指蛋白 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, Cat, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 53kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 2mg/1ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TZFP/ZNF538 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | Function: DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor. Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T cells. Subunit: Homodimer (via PTB domain). Interacts with the N-terminal of FANCC. Interacts with ZBTB16. Interacts with GATA3 (By similarity). Subcellular Location: Nucleus. Located in nuclear speckles. Tissue Specificity: Predominantly expressed in testis. Some isoforms are ubiquitously expressed. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 1 BTB (POZ) domain. Contains 3 C2H2-type zinc fingers. Database links: Entrez Gene: 27033 Human Entrez Gene: 58206 Mouse Entrez Gene: 688845 Rat Omim: 605859 Human SwissProt: Q9Y2Y4 Human SwissProt: Q9JKD9 Mouse Unigene: 99430 Human Unigene: 116789 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
DNA结合蛋白结合到5’-tGTAGTGTT-3’核心序列。可作为转录反转录激活因子和转录阻遏子。可能通过阻止GATA3与DNA结合发挥其阻遏作用。可能对辅助性T细胞的分化和活化起调节作用。