FITC标记的突触小泡蛋白P38抗体
产品名称： FITC标记的突触小泡蛋白P38抗体
英文名称： Anti-Synaptophysin/FITC
产品编号： HZ--8845R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-Synaptophysin/FITC Conjugated antibody
FITC标记的突触小泡蛋白P38抗体
| 英文名称 | Anti-Synaptophysin/FITC |
| 中文名称 | FITC标记的突触小泡蛋白P38抗体 |
| 别 名 | Major synaptic vesicle protein P38; MRXSYP; Syn p38; Synaptophysin; SYP; SYPH; SYPH_HUMAN; SypI. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 34kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Synaptophysin |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with X-linked mental retardation (XLMR). [provided by RefSeq, Aug 2011] Function: Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity. Subcellular Location: Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Cell junction > synapse > synaptosome. Tissue Specificity: Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype. Post-translational modifications: Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation. DISEASE: Defects in SYP are the cause of mental retardation X-linked SYP-related (MRXSYP) [MIM:300802]. Mental retardation is characterized by significantly below average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Similarity: Belongs to the synaptophysin/synaptobrevin family. Contains 1 MARVEL domain. Database links: Entrez Gene: 280937 Cow Entrez Gene: 6855 Human Entrez Gene: 20977 Mouse Entrez Gene: 24804 Rat Omim: 313475 Human SwissProt: P20488 Cow SwissProt: P08247 Human SwissProt: Q62277 Mouse SwissProt: P07825 Rat Unigene: 632804 Human Unigene: 223674 Mouse Unigene: 11067 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码一个完整的膜蛋白的小突触囊泡在大脑和内分泌细胞。该蛋白还结合胆固醇，并被认为直接靶向囊泡相关膜蛋白2（突触蛋白）到细胞内室。该基因的突变与X-连锁精神发育迟滞（XLMR）有关。[ RefSeq，Aug 2011提供]