FITC标记的神经元电压门控钙通道γ6抗体
产品名称： FITC标记的神经元电压门控钙通道γ6抗体
英文名称： Anti-CACNG6/FITC
产品编号： HZ-19636R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-CACNG6/FITC Conjugated antibody
FITC标记的神经元电压门控钙通道γ6抗体
| 英文名称 | Anti-CACNG6/FITC |
| 中文名称 | FITC标记的神经元电压门控钙通道γ6抗体 |
| 别 名 | a |
| 规格价格 | |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 神经生物学 信号转导 通道蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 28kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CACNG6 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Voltage-dependent calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of two known gamma subunit proteins. This particular gamma subunit is an integral membrane protein that is thought to stabilize the calcium channel in an inactive (closed) state. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members that function as transmembrane AMPA receptor regulatory proteins (TARPs). Alternative splicing results in multiple transcript variants. Variants in this gene have been associated with aspirin-intolerant asthma. [provided by RefSeq, Dec 2010] Function: Thought to stabilize the calcium channel in an inactivated (closed) state. Subunit: The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma. Subcellular Location: Plasma membrane Similarity: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. Database links: Entrez Gene: 59285 Human Entrez Gene: 54378 Mouse Entrez Gene: 140727 Rat Omim: 606898 Human SwissProt: Q9BXT2 Human SwissProt: Q8VHW3 Mouse SwissProt: Q8VHW7 Rat Unigene: 91033 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
电压依赖性钙通道由五个亚基组成。由该基因编码的蛋白质代表这些亚基之一γ，并且是两种已知的γ亚单位蛋白之一。这种特殊的伽马亚基是一种完整的膜蛋白，被认为可以稳定钙通道处于不活动（封闭）状态。该基因是PMP-22/EMP/MP20家族中功能多样的8成员蛋白亚家族的一部分，并且位于具有作为跨膜AMPA受体调节蛋白(TARP)功能的两个家族成员的簇中。选择性剪接导致多个转录变体。该基因的变体与阿司匹林不耐受哮*有关。[ RefSeq提供，DEC 2010 ]