FITC标记的神经调节蛋白3抗体
产品名称： FITC标记的神经调节蛋白3抗体
英文名称： Anti-NRG3/FITC
产品编号： HZ-6235R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-NRG3/FITC Conjugated antibody
FITC标记的神经调节蛋白3抗体
| 英文名称 | Anti-NRG3/FITC |
| 中文名称 | FITC标记的神经调节蛋白3抗体 |
| 别 名 | HRG3; Neuregulin 3; Neuregulin 3 like polypeptide; Neuregulin-3; Neuregulin3; NRG-3; Nrg3; NRG3_HUMAN; pro NRG3; Pro-NRG3. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 神经生物学 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 78kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NRG3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. Does not bind to the EGF receptor, ERBB2 or ERBB3 receptors. May be a survival factor for oligodendrocytes. Function: Direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. Does not bind to the EGF receptor, ERBB2 or ERBB3 receptors. May be a survival factor for oligodendrocytes. Subunit: Interacts with ERBB4. Subcellular Location: Pro-neuregulin-3, membrane-bound isoform: Cell membrane; Single-pass type I membrane protein. Neuregulin-3: Secreted. Isoform 3: Cell membrane; Single-pass type I membrane protein. Tissue Specificity: Highly expressed in most regions of the brain with the exception of corpus callosum. Expressed at lower level in testis. Not detected in heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, ovary, small intestine, colon and peripheral blood leukocytes. Post-translational modifications: Proteolytic cleavage close to the plasma membrane on the external face leads to the release of the soluble growth factor form. Extensive glycosylation precedes the proteolytic cleavage (By similarity). Isoform 3 is glycosylated. Similarity: Belongs to the neuregulin family. Contains 1 EGF-like domain. Database links: Entrez Gene: 10718 Human Entrez Gene: 18183 Mouse Entrez Gene: 498596 Rat Omim: 605533 Human SwissProt: P56975 Human SwissProt: O35181 Mouse Unigene: 125119 Human Unigene: 258705 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application |
ErBB4酪氨酸激酶受体的直接配体。结合导致配体刺激酪氨酸磷酸化和受体的激活。不与EGF受体、ERBB2或ERBB3受体结合。可能是少突胶质细胞的存活因子。